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. 2022 May 19;16:879513. doi: 10.3389/fnhum.2022.879513

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Copyright © 2022 Liu, Tan, Wu, Shen, Zhang, Kang, Ying, Pan, Shu and Shao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between ReHo values and emotional state. The ReHo values of specific brain regions in SM patients showed a correlation with HADS, which indicated that SM patients were more prone to be anxious and depressed. (A) ReHo values at the right middle frontal gyrus of the SM group showed a negative correlation with the AS (r = −0.961, P < 0.001). (B) ReHo values at the right fusiform gyrus of the SM group showed a positive correlation with the DS (r = 0.676, P = 0.016). ReHo, regional homogeneity; SM, severe obesity and meibomian gland dysfunction; AS, anxiety scores; DS, depression scores; HADS, hospital anxiety depression scale.