Table 3.

Main effects on cardiovascular parameters during ramp exercise.

						Blood pressure
Factors		RPE	Lactate	Glucose	Heart rate	Systolic	Diastolic	Cardiac output
		(BORG)	(mM)	(mM)	(bpm)	(mm Hg)	(mm Hg)	(mm Hg × mm Hg−1 × bpm)
Time	p-value	<0.001	<0.001	0.916	<0.001	<0.001	0.248	<0.001
	h2	0.875	0.754	0.014	0.813	0.516	0.047	0.711
Fitness_state	p-value	0.376	0.042	0.006	0.562	<0.001	0.121	<0.001
	h2	0.004	0.022	0.04	0.002	0.067	0.013	0.08
Fitness_state * time	p-value	0.359	0.174	0.588	0.957	0.999	0.288	0.301
	h2	0.041	0.054	0.03	0.011	0.003	0.045	0.044
Genotype	p-value	0.454	0.238	0.925	0.995	0.023	0.167	0.005
	h2	0.003	0.008	0	0	0.028	0.01	0.043
Genotype * time	p-value	0.254	0.807	0.934	0.98	0.842	0.457	0.67
	h2	0.047	0.02	0.013	0.008	0.018	0.035	0.026
Fitness_state * genotype	p-value	<0.001	0.07	0.006	0.005	0.023	0.38	<0.001
	h2	0.081	0.018	0.04	0.042	0.028	0.004	0.077
Fitness_state * genotype * time	p-value	0.951	0.814	0.755	0.953	0.511	0.731	0.22
	h2	0.009	0.016	0.018	0.009	0.028	0.019	0.043

Effects, which are underlined in bold, were deemed significant. Significance levels are presented without correction for multiple comparisons—based on physiological reasoning a correction factor of 3 could be stated (first: lactate, glucose/second: heart rate, systolic blood pressure, cardiac output, RPE/third: diastolic blood pressure). Repeated-measures ANOVA with post-hoc test of least significant difference for the factors exercise time × fitness state × ACE-I/D genotype (i.e., D-allele) were conducted. N = 44.