MAVS deficiency promotes kidney injury in diabetic condition. (A and B) Immunofluorescence analysis of KIM-1, a marker for tubule injury (magnification, ×200; scale bar, 50 μm). (C) NGAL concentration in the urine. (D and E) Representative kidney histology showing interstitial F4/80 macrophage infiltration (magnification, ×400; scale bar, 50 μm). (F and G) Increase in the glomerular area (magnification, ×400; scale bar, 100 μm). (H) Urinary albumin excretion (UACR) is normalized to creatinine level. Data are shown as median±IQR; *P<0.05, **P<0.01.