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. 2022 Jun;33(6):1105–1119. doi: 10.1681/ASN.2021060843

Figure 4.

Figure 4.

Hyperglycemia induced an inflammatory state in the intestine. Rorγt/Foxp3 mRNA expression normalized with β-actin in (A) the lamina propria, (B) Peyer’s patch, and (C) mesenteric lymph nodes at 18 weeks after STZ injection. Il-17 mRNA expression over 18 weeks in (D) the ileal epithelium and (E) Peyer’s patch. (F) IL-17 staining and (G) quantification in Peyer’s patch (magnification, ×200; scale bar, 50 μm) at 18 weeks of diabetes. (H) IL-17 levels in the serum. Data are shown as median±IQR; *P<0.05, **P<0.01.