Table 1.
Baseline clinical characteristics of C3G patients from cohort 1
| Variable | Value (n=89) |
|---|---|
| Age at diagnosis (yr), mean±SD | 26±21 |
| Male sex, n (%) | 48 (54) |
| C3GN/DDD, n (%) | 74/15 (83/17) |
| Autoantibodies, n (%) | |
| C3 nephritic factor | 20 (22) |
| Anti-FH | 8 (9) |
| Antecedent infection, n (%) | 22 (25) |
| Hypertension at diagnosis, n (%) | 55 (62) |
| Serum creatinine (mg/dl), median (IQR) | 1.4 (0.7–3.1) |
| eGFR at diagnosis (ml/min per 1.73 m2), median (IQR) | 55 (20–120) |
| Albumin (g/dl), mean±SD | 3±0.8 |
| Proteinuria (g/24 hr), median (IQR) | 3 (1.5–6.4) |
| Serum C3 (mg/dl), mean±SD | 63±39 |
| Serum C4 (mg/dl), mean±SD | 24±9 |
Continuous variables are presented as mean±SD, or median (IQR). DDD, dense deposit disease; IQR, interquartile range.