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. 2022 May 30;10:e13484. doi: 10.7717/peerj.13484

Table 2. Univariable logistic regression analyses, examining cognitive, psychological, sensorimotor, functional mobility, physical activity and health/disability measures as predictors of prospective falls (0 vs ≥1).

Characteristic, n (%) or mean ± SD Total Non-fallers (0) n = 160 Fallers (≥1) n = 106 OR (95% CI) p-value
Cognitive function
MMSE score 265 28.2 (1.5) 28.3 (1.5) 1.06 [0.90–1.25] 0.511
TMT-A, s 260 48.6 (16.8) 49.5 (17.6) 1.00 [0.99–1.02] 0.675
TMT-B, s 258 143.2 (70.1) 144.5 (57.1) 1.00 [1.00–1.00] 0.871
TMT-B minus TMT-A, s 258 94.6 (63.7) 94.7 (52.4) 1.00 [0.99–1.00] 0.985
FAS total responses 265 33.5 (12.1) 33.6 (11.1) 1.00 [0.98–1.02] 0.932
Digit symbol total correct 260 44.4 (11.1) 45.0 (10.3) 1.01 [0.98–1.03] 0.648
Logical memory immediate recall score 266 9.5 (3.8) 9.7 (4.1) 1.01 [0.95–1.08] 0.654
Logical memory delayed recall score 266 7.7 (3.9) 7.7 (3.9) 1.01 [0.95–1.07] 0.845
Psychological assessment
GAS score 259 1.1 (2.0) 1.2 (2.1) 1.03 [0.91–1.17] 0.626
GDS score 263 1.9 (1.9) 2.5 (2.0) 1.19 [1.04–1.36] 0.012
FESI score 266 22.7 (6.8) 24.1 (7.6) 1.03 [0.99–1.06] 0.132
Sensorimotor performance
Visual contrast sensitivity (dB) 266 20.7 (2.3) 20.1 (2.1) 0.89 [0.79–1.00] 0.045
Proprioception (degrees) 266 2.6 (1.6) 2.5 (1.5) 0.98 [0.83–1.14] 0.748
Hand reaction time (ms) 266 241.2 (45.7) 244.0 (50.4) 1.06 [0.83–1.35]a 0.640
Knee extension strength (kg) 265 27.9 (11.9) 25.9 (10.4) 0.99 [0.96–1.01] 0.169
Postural Sway (mm) 266 190 (93) 216 (94) 1.31 [1.02–1.68]a 0.033
PPA Fall Risk Score 265 0.9 (1.0) 1.2 (0.9) 1.31 [1.02–1.69] 0.037
Functional mobility and balance
Five Sit-to-Stand (s) 266 18.6 (7.5) 18.2 (7.4) 1.00 [0.99–1.00] 0.368
Timed Up and Go (s) 257 10.2 (3.2) 10.3 (3.6) 1.00 [0.98–1.01] 0.582
Coordinated Stability (errors) 263 16.0 (13.5) 17.6 (13.8) 1.01 [0.99–1.03] 0.331
Physical activity
Total (hours/wk) 241 32.5 (16.9) 28.8 (16.0) 0.99 [0.97–1.00] 0.097
Walking activity (hours/wk) 258 3.5 (4.6) 2.3 (3.8) 0.93 [0.88–1.00] 0.035
Planned (hours/wk) 248 3.7 (4.5) 2.6 (4.0) 0.94 [0.88–1.01] 0.070
Health and disability
WHODAS score 258 18.6 (6.4) 19.1 (6.8) 1.01 [0.98–1.05] 0.507

Notes:

SD, standard deviation; n, number of participants; OR, odds ratio; CI, confidence interval; MMSE, Mini-Mental State Examination; TMT-A, Trail Making Test A; TMT-B, Trail Making Test B; FAS, Controlled Oral Word Association Test responses to words beginning with F, A and S. GAS, Goldberg Anxiety Scale; GDS, Geriatric Depression Scale; FESI, Falls Efficacy Scale-International; dB, decibel; ms, milliseconds; kg, kilograms; mm, millimetres; PPA, Physiological Profile Assessment; s, second; wk, week; WHODAS, The World Health Organisation Disability Assessment Schedule. Bold p-values highlight significant findings (p < 0.05). Higher scores represent better performance for MMSE, FAS total responses, Digit symbol total correct, Logical memory immediate recall score, Logical memory delayed recall score, Melbourne Edge Test, knee extension strength, and physical activity. Lower scores represent better performance for TMT-A time score, TMT-B time score, TMT-B minus TMT-A time score, GAS, GDS, FESI, proprioception, hand reaction time, postural sway, PPA score, Sit-to-Stand time score, Timed-up-and-go, and coordinated stability.

a

OR calculated using z scores due to small unit of measurement for these variables.