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. 2022 Apr 23;13(4):10467–10481. doi: 10.1080/21655979.2022.2060787

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — LncRNA-AC093157.1 potential regulated the expression of miR-27a-3p. (a) LncRNA selection based on two databases represented by a Venn diagram, and the LncRNA-miR-27a-3p regulatory network is established by Cytoscape software. (b) Expression of AC093157.1 in ccRCC tissues and adjacent normal tissues with the matched analysis in the right. (c) MiR-27a-3p overexpression is positively related to AC093157.1 expression in ccRCC. Kaplan-Meier curves of AC093157.1 for overall and disease-specific survival (d) with ROC curve distinguishing ccRCC tissues on the right (e). The expressions of AC093157.1 (f) and miR-27a-3p (g) in the two subgroups after si-AC093157.1 transfection. q-PCR (h) and Western blot (i) analysis of ZNF268 expression in the subgroups after transfection indicating the ZNF268 regulating function. (Data represent means ± SD, ***p < 0.001 and ****p < 0.0001).