Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 20;13(4):10362–10372. doi: 10.1080/21655979.2022.2044734

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — miR-192 restrains HG-induced pyroptosis in RPE cells. ARPE-19 cells were transfected with miR-192 mimic or NC oligonucleotides after administration of HG. (a) Transfection efficiency of miR-192 overexpression was confirmed using reverse transcription-quantitative PCR. (b) PI staining was performed to determine cell death. (c) The release of LDH. (d) The activity of caspase-1. (e) MTT analysis was employed to estimate the proliferation of transfected ARPE-19 cells. (f) Western blot analysis of the expression levels of pyroptosis-associated proteins. Experimental data are presented as the mean ± SD (n = 6). **P < 0.01, ***P < 0.001. miR-192, microRNA-192; RPE cell, retinal pigment epithelial cell; HG, high glucose.