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. 2022 Apr 17;13(4):10165–10176. doi: 10.1080/21655979.2022.2060901

Figure 4.

Figure 4.

Circ_0067741 targets and regulates miR-183-5p expression in lung adenocarcinoma.

(a) ENCORI database predicted the targeting relationship between miR-183-5p and circ_0067741. (b) The combination of circ_0067741 and miR-183-5p was checked through dual-luciferase reporter assay; **P < 0.01 vs. NC mimics group. (c) qRT-PCR was for miR-183-5p expression detection in lung adenocarcinoma tissues; **P < 0.01. (d) qRT-PCR was utilized to test miR-183-5p expression in A549 and H1299 cells after transfecting; **P < 0.01 vs. siNC group, ##P < 0.01 vs. circ-NC group. (e) The relationship between circ_0067741 and miR-183-5p was analyzed through correlation analysis. Error bars stand for the mean ± SD of three independent measurements.