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. 2022 Apr 3;13(4):8759–8771. doi: 10.1080/21655979.2022.2036302

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Knockdown of circSIRT1 ameliorates PH. A: RT-qPCR test of circSIRT1 in the sh-NC and SH-CircSIRT1; B: Representative images of HE staining of rat pulmonary artery after knockdown of circSIRT1; C: Representative images of Masson staining of rat pulmonary artery after knockdown of circSIRT1; D: Hemodynamic indexes of rats after knockdown of circSIRT1; E: Immunohistochemical detection of the influence of knockdown of circSIRT1 on Beclin-1, ATG5 and P62 in rat pulmonary artery; Representation of data was as mean ± SD (n = 10); *P < 0.05.