Figure 1.

Emodin ameliorated the EAE clinical scores. (a) Clinical scores changes in NC, EAE, and emodin on 21 dpi. (b) Cumulative clinical scores of two groups on 21 dpi. Data were expressed as means ± standard deviation (n = 9). Comparisons among four groups were analyzed by one-way ANOVA on 21 dpi in A. Comparisons among four groups were analyzed by Kruskal-Wallis test using Bonferroni comparisons post hoc tests except 21 dpi in A. Comparisons among EAE, emodin-L, and emodin-H groups were analyzed by the one-way ANOVA in B. *P < 0.05, **P < 0.01 versus NC group, ^#P < 0.05, ^##P < 0.01 EAE group, and ‘ns’ stands for not significance.