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. 2022 Apr 18;13(4):9211–9231. doi: 10.1080/21655979.2022.2057896

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Expression analysis of LMNB1 in HCC. (a) LMNB1 was abnormally expressed in different malignancies in the TIMER2 database. (b) LMNB1 was upregulated in patients with high metastasis scores. (c) LMNB1 was upregulated in patients with high metastasis signatures. (d, e) In the GSE14520 dataset (d) and TCGA-LIHC dataset (e), LMNB1 was overexpressed in HCC compared to peritumoral tissues. (f) Representative IHC images of HCC tissues and peritumoral tissues. IHC verified that LMNB1 was overexpressed in HCC. Scale bars (up) = 100 μm. Scale bars (low) = 50 μm. (g) Overexpression of LMNB1 was detected in HCC cell lines. (h) Western blot analysis of HCC tissues and peritumoral tissues. *P < 0.05, **P < 0.01, ***P < 0.001.