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. 2022 Mar 22;13(4):8000–8012. doi: 10.1080/21655979.2022.2048991

Figure 5.

Figure 5.

UBE2B overexpression-induced ovarian cancer growth is hampered by ZMYM2 knockdown. (a-f) Representative images (a, b, and e) and quantitation (c and f) of colonies formed by CAOV4 cells with UBE2B knockdown (a and c) or overexpression (b-c), or ZMYM2 knockdown (d-f). n = 3 per group. (g,i) Representative images (g) and quantitation of tumor weight (i) of xenograft tumors derived from CAOV4 cells with UBE2B overexpression alone, ZMYM2 knockdown alone, or in combination. n = 6 per group. (h,j) Representative images (h) and quantitation of the Ki-67 positive cells (j) of xenograft tumors derived from CAOV4 cells with UBE2B overexpression alone, ZMYM2 knockdown alone, or in combination. n = 6 per group. *, p < 0.05; **, p < 0.01; ***, p < 0.001.