Figure 1.

DHI improves DN.

(a) Blood glucose test every 4 weeks; (b) weight check every 4 weeks; (c) creatinine measurement at 24 weeks of age; (d) urea nitrogen detected at 24 weeks of age; (e-g) inflammatory markers IL-6, IFN-γ and TNF-α contents in serum of db/db mice; (h) the pathological condition of renal tissues detected via HE staining; (i) the renal tissue apoptosis detected via TUNEL staining. The data were expressed as mean ± SEM, (a&b) n = 10; C-I, n = 5; * P < 0.05, versus db/m; # P < 0.05, versus db/db control.