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. 2022 May 10;50(1):87. doi: 10.3892/ijmm.2022.5143

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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PGP9.5 expression in the Control, DM, DM + A and DM + B groups, as determined via immunohistochemical analysis. Nuclei and PGP9.5 were labeled as blue and brown, respectively. A rat model of DM was established using an intraperitoneal injection of streptozotocin. The rats in the Control group were given an equal volume of citric acid solvent. Magnification, ×200. ^*P<0.05 vs. Control; ^#P<0.05 vs. DM. DM, diabetes mellitus model; DM + A, diabetic rats treated with 5 µg/kg prucalopride; DM + B, diabetic rats treated with 10 µg/kg prucalopride; PGP9.5, ubiquitin thiolesterase.