Table 2:

Summary of group differences in cerebellar volumes (mm³). Hypothesis tests assess mean group differences after adjusting for age, sex, race, and total brain volumes and after correcting for multiple testing. ROI-specific effect sizes (Cohen’s d) are provided in Figure 3 and Table S1.

Left ROI		TD	22q11DS	F	p-value	Right ROI	TD	22q11DS	F	p-value
Anterior						Anterior
Lobe	Mean	8823.83	7833.12	47.463	<0.0001	Lobe	8275.75	7057.69	88.27	<0.0001
	SD	1028.41	1025.85				995.72	866.06
	SEM	15.12	12.99				14.64	10.96
SPL	Mean	33278.83	27674.26	134.31	<0.0001	SPL	37834.73	31552.03	150.20	<0.0001
	SD	3177.50	3642.61				3594.83	4096.93
	SEM	46.73	46.11				52.87	51.86
IPL	Mean	14883.77	12303.44	139.67	<0.0001	IPL	12857.11	10860.98	95.66	<0.0001
	SD	1725.89	1594.72				1545.03	1316.93
	SEM	25.38	20.19				22.72	16.67
Lobules I/II	Mean	73.88	61.78	14.89	0.0002	Lobules I/II	96.80	81.02	22.07	<0.0001
	SD	20.39	15.84				24.38	17.19
	SEM	0.30	0.20				0.36	0.22
Lobule III	Mean	953.60	805.01	55.42	<0.0001	Lobule III	1060.04	866.00	73.60	<0.0001
	SD	129.32	132.98				145.54	136.99
	SEM	1.90	1.68				2.14	1.73
Lobule IV	Mean	2983.07	2681.60	19.54	<0.0001	Lobule IV	2312.40	2018.44	33.04	<0.0001
	SD	459.30	430.14				376.73	320.11
	SEM	6.75	5.44				5.54	4.05
Lobule V	Mean	4887.16	4346.51	47.49	<0.0001	Lobule V	4903.31	4173.26	83.10	<0.0001
	SD	569.39	577.23				613.63	524.09
	SEM	8.37	7.31				9.02	6.63
Lobule VI	Mean	9273.15	7864.90	88.07	<0.0001	Lobule VI	10135.19	8548.65	85.99	<0.0001
	SD	1079.80	1118.60				1240.64	1184.91
	SEM	15.88	14.16				18.24	15.00
Crus I	Mean	11725.35	9730.58	73.69	<0.0001	Crus I	12697.33	10847.62	66.11	<0.0001
	SD	1343.88	1597.03				1442.56	1622.81
	SEM	19.76	20.22				21.21	20.54
Crus II	Mean	8149.74	6718.33	84.46	<0.0001	Crus II	9519.20	7713.11	138.43	<0.0001
	SD	999.71	1025.15				1014.38	1191.68
	SEM	14.70	12.98				14.92	15.08
Lobule VIIB	Mean	4130.60	3360.46	93.16	<0.0001	Lobule VIIB	5483.02	4442.65	116.28	<0.0001
	SD	531.21	516.93				695.57	645.78
	SEM	7.81	6.54				10.23	8.17
Lobule VIIIA	Mean	6672.00	5429.93	139.43	<0.0001	Lobule VIIIA	5044.03	4134.08	94.93	<0.0001
	SD	815.62	799.24				692.73	639.38
	SEM	11.99	10.12				10.19	8.09
Lobule VIIIB	Mean	4136.13	3480.32	70.56	<0.0001	Lobule VIIIB	3833.13	3393.11	44.53	<0.0001
	SD	645.78	520.76				525.55	422.18
	SEM	9.50	6.59				7.73	5.34
Lobule IX	Mean	4075.64	3393.19	47.82	<0.0001	Lobule IX	3979.95	3333.79	48.84	<0.0001
	SD	662.45	508.75				618.76	465.23
	SEM	9.74	6.44				9.10	5.89
Lobule X	Mean	709.48	640.93	25.25	<0.0001	Lobule X	701.01	632.27	22.59	<0.0001
	SD	91.76	83.05				101.85	83.89
	SEM	1.35	1.05				1.50	1.06
White Matter	Mean	10133.51	8581.70	137.89	<0.0001	White Matter	9605.41	8114.96	132.90	<0.0001
	SD	878.02	1060.71				867.91	998.13
	SEM	12.91	13.43				12.76	12.63