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. 2022 Jun 2;13:3088. doi: 10.1038/s41467-022-30705-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The log-inverse RMSF vs local dimensionality for each residue in i unglycosylated antibody CH2 domain, ii Oestrogen Related Receptor g. b The positive correlation (0.539) between local dimension and log-inverse RMSF at the residue level across 12 different proteins as a function of scale. c A strong positive correlation between global dimensionality of 12 proteins against log-inverse RMSF. d The local dimension of each residue mapped onto Aquifex Adenylate Kinase in the open (PDB ID: 2RH5) and closed (PDB ID: 2RGX) conformations and e plotted by residue id.