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. 2022 Feb 3;20(1):589–598. doi: 10.1007/s40201-021-00783-x

Table 4.

Factors affecting the incidence of effects

Remarks Ref.
Higher levels of triclosan have been reported in the serum of men than women. [59]
.An increase in urinary MEP was observed in men who used cologne [7]
Higher levels of monobutyl phthalate (MBP), monoethyl phthalate (MEP), and mono-2-ethylhexyl phthalate (MEHP) in women’s urine was found to be more than men which suggests more exposure to dibutyl phthalate (DBP), diethyl phthalate (DEP), and di- (2-ethylhexyl) phthalate (DEHP) due to the use of perfumes and colognes. [42]
The amount of triclosan observed in the urine of people aged 31 to 45 years was higher than other age groups. [59]
People above the age of 25 are more exposed to triclosan than those below the age of 25. [17]
According to a national survey, Africans, Americans and Hispanics had higher levels of MEP and MBP in their urine than Caucasians in the face of perfume contaminants. [7]
There is a direct relationship between the habit of daily use of people and less use of perfume with the amount of urinary MEP. [44]
The rate at which a chemical compound is absorbed into the skin depends on its properties, such as lipophilicity, molecular weight, and volatility. [29]
Aluminum chlorohydrate, which is an axillary antiperspirant compound, is absorbed from intact skin and stripped skin 1.81 μg/cm2 and 11.5 μg/cm2, respectively. [45]
D4 and D5 were absorbed from the axillary skin within 1 h and observed in the blood so that the maximum absorption of D4 was 0.12% of the dose for men, 0.3% for women and 0.05% for D5 in women and men. [45]