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. 2022 May 20;13:898022. doi: 10.3389/fneur.2022.898022

Table 4.

Comparison of two groups who never smoked vs. those who smoked/exposed.

Variables Smokers (n = 154) Nonsmokers (n = 55) p
Age (Mean, SD) 40.64 (11.43) 37.55 (10.64) 0.073
Female/Male (n,%) 19 (12.3%) 135 (87.7%) 14 (25.5%) 41 (74.5%) 0.030
Episodic Cluster Headache (n,%) 135 (87.7%) 50 (90.9%) 0.627
Chronic Cluster Headache (n,%) 19 (12.3%) 5 (9.1%)
Age at onset (years) (Mean, SD) 28.66 (10.74) 28.27 (8.84) 0.795
Age at correct diagnosis (years)
(Mean, SD)
33.84 (11.64) 32.52 (9.71) 0.411
Family history with CH (n, %) 17 (11.0%) 2.0 (3.6%) 0.169
Family history with heart diseases (n,%) 65 (42.2%) 5 (9.1%) <0.001
Head trauma before the diagnosis (n,%) 21 (13.6%) 0.0 (0%) 0.001
NAS (Mean, SD) 8.78 (1.3) 8.58 (1.23) 0.316
Nasal congestion (n,%) 92 (59.7%) 23 (41.8%) 0.027
Pain location (behind eyes) (n,%) 139 (90.3%) 50 (90.9%) 0.564
Pain location (temple) (n,%) 107 (69.5%) 28 (50.9%) 0.021
Improvement with both O2 and triptan (n,%) 62 (52.1%) 14 (32.6%) 0.033

n, number of subjects; SD, Standard deviation; CH, Cluster Headache; NAS, Numeric Analog Scale; O, Oxygen, bold means p < 0.05;

*

Unpaired t-test.