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. 2022 May 20;13:849468. doi: 10.3389/fimmu.2022.849468

Table 3.

Patients’ chemotherapy for all patients according to programmed cell death ligand-1 (PD-L1).

n level Low PDL-1 High PD-L1 P
61 43
Neoadjuvant chemotherapy regimen (%) AC/ACF 3 (4.9) 1 (2.3) 0.754
CT/ACT 7 (11.5) 3 (7.0)
AT 28 (45.9) 25 (58.1)
TP 13 (21.3) 8 (18.6)
Others 10 (16.4) 6 (14.0)
Duration of neoadjuvant therapy (%) <6 16 (26.2) 18 (41.9) 0.144
≥6 45 (73.8) 25 (58.1)
Response (%) PR 38 (62.3) 22 (51.2) 0.326
SD 22 (36.1) 21 (48.8)
PD 1 (1.6) 0 (0.0)
MPG (%) 1 7 (11.5) 2 (4.7) 0.568
2 24 (39.3) 18 (41.9)
3 26 (42.6) 22 (51.2)
4 1 (1.6) 0 (0.0)
5 3 (4.9) 1 (2.3)
Postoperative chemotherapy (%) No 22 (36.1) 8 (18.6) 0.086
Yes 39 (63.9) 35 (81.4)
Postoperative chemotherapy regimen (%) AC/ACF 7 (11.5) 2 (4.7) 0.068
CT/ACT 1 (1.6) 5 (11.6)
AT 6 (9.8) 3 (7.0)
TP 9 (14.8) 8 (18.6)
Others 16 (26.2) 17 (39.5)
NO 22 (36.1) 8 (18.6)
Postoperative chemotherapy times (%) <4 36 (59.0) 12 (27.9) 0.003
≥4 25 (41.0) 31 (72.1)

A, Anthracyclines; C, Cyclophosphamide; F, 5-Fluorouracil; T, Taxol; P, Platinum compounds.