Table 1.
Summary of the patient characteristics in different cohorts in terms of clinical variables.
| Parameter | Training D1 | Validation D2 | |
|---|---|---|---|
| Cohort 1 | Cohort 2 | Cohort 3 | |
| N (patients) | 71 | 42 | 20 |
| N (BCR+) | 27 | 5 | 8 |
| N (BCR−) | 44 | 37 | 12 |
| Median age (range), years | 59 (47–79) | 64 (42–76) | 61 (47–86) |
| Mean PSA (range), ng/ml | 10 (1–58) | 10.6 (1.8–88.3) | 9 (1.2–69.4) |
| Lesion volume (cm3) | 3.93 ± 6.47 | 3.34 ± 5.13 | 2.20 ± 5.05 |
| Prostate volume (cm3) | 35.65 ± 12.37 | 38.81 ± 19.04 | 40.83 ± 16.99 |
| Follow-up (months) | 43 ± 28 | 30 ± 24 | 33 ± 18 |
| biopsy Gleason Grade Group and RP Gleason Grade Group (N) | |||
| 1 | 15 | 7 | 3 |
| 2 | 20 | 27 | 6 |
| 3 | 8 | 13 | 5 |
| 4 | 10 | 3 | 4 |
| 5 | 18 | 6 | 2 |
| RP pGG | |||
| 1 | 6 | 4 | 3 |
| 2 | 22 | 24 | 8 |
| 3 | 13 | 15 | 4 |
| 4 | 7 | 3 | 2 |
| 5 | 18 | 10 | 3 |
| PI-RADS-v2.0 | |||
| 1 | 0 | 1 | 0 |
| 2 | 10 | 8 | 2 |
| 3 | 6 | 3 | 2 |
| 4 | 21 | 10 | 6 |
| 5 | 34 | 34 | 10 |
| EPE | |||
| Yes | 33 | 21 | 8 |
| No | 30 | 21 | 12 |
| N/A | 8 | 0 | 0 |
| SVI | |||
| Yes | 24 | 5 | 4 |
| No | 42 | 37 | 16 |
| N/A | 5 | 0 | 0 |
| PSM | |||
| Yes | 0 | 20 | 6 |
| No | 0 | 22 | 14 |
| N/A | 71 | 0 | 0 |
| LNI | |||
| Yes | 12 | 15 | 1 |
| No | 41 | 22 | 18 |
| N/A | 18 | 5 | 1 |
| Decipher risk | |||
| Low | N/A | 20 | N/A |
| Intermediate | N/A | 5 | N/A |
| High | N/A | 17 | N/A |
BCR, biochemical recurrence; RP, radical prostatectomy ;PI-RADS, Prostate Imaging Reporting and Data System; EPE, Extra Prostatic Extension; SVI, Seminal Vesicle Invasion; PSM, Positive Surgical Margin; LNI , Lymph Node Invasion; N/A, Not Available.