Table 6.
Comparison of the integrated radiomic model CS +R with post-surgical variables, nomograms CAPRA and CAPRA-S, and Decipher risk scores on the validation set (N = 62, NBCR+ = 13, NBCR− = 49).
| Parameter | HR | Lower 0.95 CI | Upper 0.95 CI | C-index | p-value |
|---|---|---|---|---|---|
| CS +R | 2.1 | 0.35 | 11.33 | 0.76 | 0.03 |
| Pathologic GG | 2.6 | 1.16 | 5.93 | 0.82 | 0.01 |
| EPE | 2.5 | 1.06 | 11.26 | 0.66 | 0.04 |
| SVI | 0.8 | 0.24 | 2.57 | 0.49 | 0.7 |
| PSM | 2.9 | 1.32 | 30.2 | 0.71 | 0.03 |
| CAPRA | 1.8 | 1.1 | 3.56 | 0.69 | 0.02 |
| CAPRA-S | 2.1 | 1.2 | 5.72 | 0.75 | 0.03 |
| Decipher | 1.4 | 0.61 | 2.45 | 0.59 | 0.18 |
GG, Gleason grade; EPE, extraprostatic extension; SVI, seminal vesicle invasion; PSM, positive surgical margins; CAPRA, Cancer of the Prostate Risk Assessment (UCSF nomogram); CAPRA-S, post-surgical CAPRA. The p-values in bold indicate statistical significance.