TABLE 1.
Clinical characteristics of the study patients in NF, SF, and AF groups.
| Characteristics | NF (n = 16) | SF (n = 23) | AF (n = 9) | p-value | ||
|---|---|---|---|---|---|---|
| NF vs. SF | NF vs. AF | SF vs. AF | ||||
| Age/year | 47.0 (41.5–51.8) | 52.2 (46.0–55.2) | 52.1 (48.0–57.0) | 0.267 | 0.156 | 0.579 |
| Female, n (%) | 10 (62.5) | 17 (73.9) | 8 (88.9) | - | - | - |
| ALT/U L−1 | 69.0 (18.8,126.8) | 159.0 (55.0–298.5) | 143.0 (78.0–173.0) | 0.273 | 0.877 | 0.236 |
| AST/U L−1 | 25.0 (19.0–170.3) | 111.0 (72.0–290.5) | 132.0 (101.0–267.0) | 0.124 | 0.085 | 0.743 |
| AST/ALT | 1.0 (0.6–1.4) | 0.7 (0.5–1.9) | 1.4 (0.7–2.2) | 0.296 | 0.155 | 0.567 |
| ALP/U L−1 | 104.0 (65.0–127.0) | 104.0 (85.5,135.5) | 108.0 (102.0–123.0) | 0.853 | 0.461 | 0.375 |
| GGT/U L−1 | 118.0 (35.8,161.8) | 83.0 (54.5,156.5) | 148.0 (102.0–240.0) | 0.396 | 0.734 | 0.145 |
| ALB/g L−1 | 39.0 (37.5–40.3) | 36.0 (34.0–37.5) | 35.0 (35.0–35.0) | 0.011 | 0.001 | 0.070 |
| TBIL/µmo L−1 | 12.0 (9.6–18.8) | 14.3 (9.2–37.4) | 49.3 (27.0–53.3) | 0.622 | 0.657 | 0.908 |
| DBIL/µmo L−1 | 4.6 (3.6–7.6) | 8.7 (3.9–30.3) | 35.5 (8.5–43.7) | 0.554 | 0.562 | 0.954 |
| CHE/U L−1 | 6978.5 (5407.8–7850.8) | 5511.0 (4502.5–6957.5) | 5550.0 (4220.0–6134.0) | 0.205 | 0.052 | 0.542 |
| TC/mmol L−1 | 4.5 (3.7–5.3) | 3.6 (3.2–4.7) | 4.0 (2.9–4.4) | 0.172 | 0.191 | 0.956 |
| TG/mmol L−1 | 1.4 (1.2–1.8) | 1.6 (0.9–2.1) | 1.6 (1.3–2.3) | 0.866 | 0.268 | 0.159 |
| IgA/g L−1 | 2.2 (1.4–2.4) | 2.1 (1.7–2.8) | 2.0 (1.6–3.2) | 0.324 | 0.375 | 0.772 |
| IgG/g L−1 | 12.6 (8.9–15.8) | 14.8 (12.5–18.2) | 12.6 (11.7–14.7) | 0.108 | 0.825 | 0.289 |
| IgM/g L−1 | 0.9 (0.7–1.3) | 1.1 (0.7–1.2) | 0.9 (0.5–1.0) | 0.835 | 0.525 | 0.537 |
| INR/IU | 1.0 (0.9–1.0) | 1.0 (0.9–1.1) | 1.0 (0.9–1.1) | 0.170 | 0.112 | 0.490 |
| CRE/µmo L−1 | 66.0 (56.0–75.8) | 60.0 (51.0–67.5) | 58.0 (52.0–66.0) | 0.081 | 0.326 | 0.894 |
| PT/s | 11.0 (10.7–11.4) | 11.1 (10.6–12.2) | 11.6 (10.8–12.8) | 0.135 | 0.103 | 0.504 |
ALT, alanine aminotransferase; AST, aspartate transaminase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; ALB, albumin; TBIL, total bilirubin; DBIL, direct bilirubin; CHE, cholinesterase; TC, total cholesterol; TG, triglyceride; INR, International standard ratio; CRE, creatinine; PT, prothrombin time. NF, nonsignificant fibrosis; SF, significant fibrosis; AF, advanced fibrosis.
Data are median (p25, p75) or numerical value. p-values for comparisons were carried out by nonparametric tests.