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(A) Schematic illustration of the synthesis of CuTA nanozyme. (B) Schematic illustration of the synthesis of enzymatically crosslinked CuTA@SF hydrogel and the reasonable form of intermolecular connection inside CuTA@SF hydrogel. (C) In the osteochondral defect model of rabbits, the implantation of CuTA@SF hydrogel promoted cell proliferation, BMSC differentiation and ECM deposition. Moreover, CuTA@SF hydrogel had antioxidant, anti-inflammation and antibacterial capacities.
