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. 2022 May 20;3:887541. doi: 10.3389/fgwh.2022.887541

Table 2.

Estradiol results expressed as median values (interquartile range).

DMPA-IM Copper IUD LNG implant DMPA vs. IUD DMPA vs. implant Implant vs. IUD
E2 pmol/L n Median IQR n Median IQR n Median IQR p p p
Baseline 131 229 152–455 135 235 168–426 134 216 153–419 0.89 0.80* 0.40*
6 months 131 139 97–193 135 298 163–467 132 156 112–250 <0.0001* 0.005 0.004
P (change from baseline) <0.0001* 0.51 0.0002*

E2, estradiol; DMPA, depot medroxyprogesterone acetate; IUD, intrauterine device; LNG, levonorgestrel; CI, confidence interval; IQR, interquartile range; * Mann Whitney U test.