Table 2.
DMPA-IM | Copper IUD | LNG implant | DMPA vs. IUD | DMPA vs. implant | Implant vs. IUD | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
E2 pmol/L | n | Median | IQR | n | Median | IQR | n | Median | IQR | p | p | p |
Baseline | 131 | 229 | 152–455 | 135 | 235 | 168–426 | 134 | 216 | 153–419 | 0.89 | 0.80* | 0.40* |
6 months | 131 | 139 | 97–193 | 135 | 298 | 163–467 | 132 | 156 | 112–250 | <0.0001* | 0.005 | 0.004 |
P (change from baseline) | <0.0001* | 0.51 | 0.0002* |
E2, estradiol; DMPA, depot medroxyprogesterone acetate; IUD, intrauterine device; LNG, levonorgestrel; CI, confidence interval; IQR, interquartile range; * Mann Whitney U test.