TABLE 5.

Risk prediction score performance for iBox when assessed in different clinical scenarios and subpopulations (9).

Risk score performance assessment	Risk model performance (C-statistic)	95% bootstrap percentile CI
Functional and immunological parameters (without histology)	0.79	(0.77–0.81)
Histology diagnoses instead of Banff lesions grading	0.76	(0.74–0.81)
Stable patients (protocol biopsy)	0.81	(0.77–0.86)
Unstable patients (indication biopsy)	0.80	(0.78–0.82)
First year post-transplant	0.77	(0.72–0.81)
After 1 year post-transplant	0.84	(0.82–0.87)
Living donors	0.82	(0.75–0.88)
Deceased donors	0.80	(0.78–0.82)
Highly sensitized recipients	0.80	(0.76–0.84)
Non–highly sensitized recipients	0.81	(0.79–0.83)
Adding transplant baseline characteristics‡	0.81	(0.79–0.83)
Patients with anti-IL-2 receptor induction	0.79	(0.76–0.82)
Patients with antithymocyte globulin induction	0.83	(0.80–0.85)
African American population	0.80	(0.74–0.85)
Non-African American population	0.84	(0.80–0.89)
Recipient blood pressure profile post-transplant	0.80	(0.78–0.82)
Calcineurin inhibitor blood level at time of evaluation	0.81	(0.78–0.83)

CI, confidence interval; eGFR, estimated glomerular filtration rate; IL, interleukin.