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Distribution of homogeneity (upper panel) and fractional anisotropy (lower panel) in callosal areas I – V for classical amyotrophic lateral sclerosis (ALS) and its phenotypes (restricted phenotypes primary lateral sclerosis (PLS), flail arm syndrome (FAS), progressive bulbar palsy (PBP), lower motor neuron disease (LMND)) (red) compared to controls (blue). The overlap of distributions is shaded in grey. A small overlap represents a good separation of both groups.
