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. 2022 Mar 23;44(4):1452–1462. doi: 10.3390/cimb44040097

Figure 2.

Figure 2

Impact of folate supplementation on markers of genomic damage, measured through CBMN assay in a human lymphoblastoid cell line. (a) Study design. (b) Effect of FA media concentration on micronuclei occurrence. (c) Effect of FA media concentration on the incidence of nucleoplasmic bridges. (d) Effect of FA media concentration on nuclear budding. (e) Media FA levels impact the incidence of micronuclei in LCLs exposed to hydrogen peroxide. (f) Media FA levels impact the incidence of nucleoplasmic bridges in LCLs exposed to hydrogen peroxide. (g) Media FA levels impact the incidence of nuclear budding in LCLs exposed to hydrogen peroxide. Results are from technical triplicates (n = 3). Bars, SEMs, and means with different letters (a,b,c,d) are significantly different (Tukey’s HSD, p < 0.05).