Table 2.

Expression levels (relative quantification, RQ) of circRNA 0001345, miRNA 106b, and mRNA ATG16L1 among the investigated groups of rats.

Groups	CircRNA 0001345	miRNA 106b	mRNA ATG16L1
	Fold Change Levels
Normal control	0.91 ± 0.15	1.05 ± 0.20	1.46 ± 0.24
PCL	0.5 ± 0.11	22.34 ± 2.13 a	0.08 ± 0.01
T1	2.67 ± 0.30	0.6 ± 0.08 b	3.84 ± 0.42
T2	5.82 ± 0.61 b	0.23 ± 0.06 b	12.64 ± 1.76 b,c
T3	23.37 ± 2.51 b,c,d	0.21 ± 0.03 b	19.66 ± 1.81 b,c,d

PCL, precancerous lesion group; T1, group treated with 10 mg/kg C3G; T2, group treated with 15 mg/kg C3G; and T3, group treated with 20 mg/kg C3G. Data were expressed as mean ± SD. The number of rats equals six for each group. ^a significant difference from the normal control group, ^b significant difference from the PCL group, ^c significant difference from the T1 group, ^d a significant difference from the T2 group. Specimen, liver tissue.