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Subfamilies of the G3E P-Loop GTPases
| Subfamily | Known roles | Known metals/metallocofactor |
|---|---|---|
| UreG | Maturation of ureases | Nickel |
| HypB | Maturation of [NiFe]-hydrogenases | Nickel |
| MeaB | Maturation of adenosylcobalamin-dependent mutases | Cobalamin |
| COG0523 | Zinc homeostasis (ZigA/ZagA), Nitrile hydratase maturation (Nha3), Cobalamin cofactor biosynthesis (CobW) |
Zinc Iron Cobalt |
