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. 2022 Jun 3;6(4):e12736. doi: 10.1002/rth2.12736

TABLE 3.

Treatment characteristics

Enoxaparin Dalteparin or tinzaparin
Patients, N 3526 925
Switching LMWH doses
Yes, n (%) 1215 (34) 197 (21)
Number of days until switch
Mean days ±SD 17 ± 27 28 ± 28
Median days (min‐max) 8 (1‐178) 27 (1‐150)
Changes of daily doses, n (%)
Increase in doses 225 (6.4) 46 (5.0)
Decrease in doses 1095 (31) 172 (19)
Both increase and decrease 105 (3.0) 21 (2.3)
Number of doses switch
1 1027 (29) 173 (19)
2 134 (3.8) 18 (1.9)
≥3 54 (1.5) 6 (0.65)
Regimen, n (%)
Once daily 891 (25) 925 (100)
Twice daily 1856 (53) 0
Regimen modification
Twice daily to once daily 687 (20) 0
Once daily to twice daily 42 (1.2) 0
Multiple dosing changes 50 (1.4) 0
Different drugs 0 49 (5.3)

Abbreviations: LMWH, low‐molecular‐weight heparin; SD, standard deviation.