Table 2.
Univariate and multivariate cox regression model of overall survival for advanced PBTC
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Age | ||||||
| < 65 | Ref | |||||
| ≥ 65 | 1.491 | 1.324–1.678 | 0.000 | 1.355 | 1.202–1.528 | 0.000 |
| Sex | ||||||
| Male | Ref | |||||
| Female | 0.945 | 0.841–1.061 | 0.339 | |||
| Race | ||||||
| White | Ref | |||||
| Black | 1.041 | 0.89–1.218 | 0.612 | |||
| Others | 0.987 | 0.783–1.244 | 0.912 | |||
| Grade | ||||||
| I (Well) | Ref | |||||
| II (Moderately) | 2.328 | 1.913–2.832 | 0.000 | 2.280 | 1.863–2.790 | 0.000 |
| III (Poorly) | 3.159 | 2.597–3.844 | 0.000 | 2.854 | 2.326–3.502 | 0.000 |
| IV (Undifferentiated) | 2.379 | 1.589–3.561 | 0.000 | 2.419 | 1.610–3.636 | 0.000 |
| AJCC stage | ||||||
| III | Ref | |||||
| IV | 1.306 | 1.126–1.514 | 0.000 | |||
| T stage | ||||||
| T1 | Ref | |||||
| T2 | 1.755 | 1.175–2.620 | 0.006 | 1.029 | 0.687–1.540 | 0.891 |
| T3 | 1.246 | 0.837–1.856 | 0.279 | 0.941 | 0.629–1.408 | 0.769 |
| T4 | 1.393 | 0.937–2.069 | 0.101 | 0.955 | 0.633–1.442 | 0.827 |
| N stage | ||||||
| N0 | Ref | |||||
| N1 | 0.953 | 0.846–1.073 | 0.424 | 1.246 | 1.101–1.409 | 0.000 |
| M stage | ||||||
| M0 | Ref | |||||
| M1 | 1.306 | 1.126–1.514 | 0.000 | 1.233 | 1.017–1.494 | 0.033 |
| Surgery | ||||||
| No | Ref | |||||
| Yes | 0.337 | 0.290–0.391 | 0.000 | 0.350 | 0.297–0.413 | 0.000 |
| Radiotherapy | ||||||
| No | Ref | |||||
| Yes | 0.735 | 0.618–0.873 | 0.000 | 0.891 | 0.740–1.072 | 0.221 |
| Chemotherapy | ||||||
| No | Ref | |||||
| Yes | 0.972 | 0.858–1.102 | 0.662 | 0.699 | 0.612–0.798 | 0.000 |
PBTC pancreatic body tail cancer, HR hazard ratio, CI confidence intervals AJCC American joint committee on cancer