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. 2022 Jun 3;22:377. doi: 10.1186/s12888-022-04016-9

Table 2.

Patient demographic and clinical characteristics

N = 320
Demographics at start of selected treatment episodea
Age
  Mean ± SD 29.3 ± 10.7
  Median 26.9
  IQR (19.3, 36.9)
Gender (%)
  Male 65.0%
  Female 34.7%
  Non-binary 0.3%
Race (%)
  American Indian or Alaska Native 1.3%
  Asian 8.4%
  Black or African American 11.3%
  Native Hawaiian or Other Pacific Islander 0.0%
  White or Caucasian 76.9%
  Other 1.6%
  Unknown 0.6%
Ethnicity (%)
  Hispanic or Latino 5.9%
  Not Hispanic or Latino 91.3%
  Unknown 2.8%
Region of residence (%)
  Midwest 27.8%
  Northeast 22.2%
  South 31.6%
  West 18.4%
Type of healthcare coverage (%)
  Commercial/private insurance 76.9%
  Medicare 3.1%
  Medicaid 15.3%
  Military insurance (VA or active military) 2.8%
  Other 0.0%
  No insurance 1.3%
  Unknown 2.8%
Duration of treatment history available (%)
  0–1 years 12.2%
  2–3 years 39.1%
  4–5 years 22.5%
   ≥ 5 years 26.3%
Clinical disease characteristics
Type of ADHD (%)
  Inattentive 50.0%
  Combined presentation 42.2%
  Hyperactive 7.2%
  Unknown 0.6%
   Age at first diagnosis (%)
  Child 20.3%
  Adolescent 22.2%
  Adult 57.5%
Time from first diagnosis to treatment initiation (%)
  Less than 1 year 12.5%
  1–5 years 44.1%
  5–10 years 17.8%
  10–15 years 10.9%
   ≥ 15 years 14.7%
Overall disease severityb at time of treatment initiation (%)
  Mild 11.3%
  Moderate 75.6%
  Severe 10.9%
  Unknown 2.2%
Most frequent comorbidities associated with ADHD (%)
  Anxiety 31.6%
  Depression 14.1%
  Insomnia/sleep disturbances 10.9%
  Emotional impulsivity/lability/dysregulation 10.6%
  Learning disability 5.3%
Most frequent other comorbidities (%)
  Obesity 6.6%
  Diabetes without chronic complications 2.5%
  Liver disease, mild 1.6%
  Chronic pulmonary disease 1.3%
  Peptic ulcer disease 1.3%

ADHD Attention-deficit/hyperactivity Disorder, AE Adverse Event, SD Standard Deviation, IQR Interquartile Range, VA Veteran Affairs

a All patients were alive as of the date of chart abstraction

b Disease severity was determined by clinical judgement in 45% of physicians, and the remaining physicians reported using ADHD rating scales, including the Adult ADHD Clinical Diagnostic Scale (ACDS), Adult ADHD Self-Report Scale (ASRS), ADHD Rating Scale IV and/or 5 (ADHD-RS-IV and/or ADHD-RS-5), Adult ADHD Investigator Symptom Rating Scale (AISRS)