Table 3.
Tumor Histology, Best Response, and Biomarkers
| Tumor Histology | FATSI | PD-L1 Score | TMB Score | Response |
|---|---|---|---|---|
| Ovarian (Papillary Serous) | Negative | N/A | N/A | PR |
| Esophagus Squamous | Negative | N/A | Intermediate | SD |
| Endometrial | Negative | Negative|0% | 9 muts/Mb | CR |
| Endometrial | Negative | Negative|0% | 7 muts/Mb | SD |
| Endometrial | Negative | N/A | N/A | PR |
| Adenoid Cystic Carcinoma | Negative | N/A | 7 muts/Mb | PD |
| Endometrium | Negative | N/A | N/A | CR |
| Vaginal | Negative | N/A | N/A | PD |
| Endometrium | Negative | N/A | N/A | PR |
| Colon | Negative | Negative|0% | 9 muts/Mb | PD |
| Endometrial | Negative | Negative|0% | 7 muts/Mb | PD |
| Endometrial | Negative | N/A | 5 muts/Mb | PD |
| Endometrial | Negative | Negative|0% | 14 muts/Mb | SD |
| Endometrial | Negative | N/A | N/A | SD |
| Endometrial | Negative | CPS >/= 1 | N/A | PR |
| Endometrial | Negative | Negative|0% | 6 muts/Mb | PD |
| Colon | Positive | N/A | NA | PD |
| Thymic | Positive | N/A | Low/3.5 | SD |
| Ovarian | Positive | N/A | N/A | PD |
| Ovarian | Positive | N/A | N/A | PD |
| Fallopian Tube | Positive | N/A | N/A | PD |
| Cervical Squamous | Positive | N/A | High | PR |
| Pancreatic | Positive | N/A | N/A | PD |
| Endometrial Carcinosarcoma | Positive | Negative | Low/4 | PD |
| Cervical Squamous | Positive | N/A | N/A | SD |
| Fallopian tube | Positive | N/A | N/A | SD |
| Pancreatic | Positive | N/A | Intermediate | PD |
| Endometrial | Positive | Negative | Low/6 | PD |
| Ovarian (Serous) | Positive | Negative | Low/4 | PD |
| Ovarian | Positive | N/A | N/A | SD |
| Breast | Positive | N/A | 7.9 muts/Mb | SD |
| Ovarian (Serous) | Positive | N/A | 10 muts/Mb | PD |
| Mullerian Remnant Papillary Serous | Positive | Negative|0% | 6 muts/Mb | SD |
| Ovarian | Positive | N/A | N/A | NE |
| Neuroendocrine Colorectal | Positive | N/A | N/A | PD |
| Ovarian | Positive | N/A | N/A | PD |
| Ovarian | Positive | Negative|1+, 2% | N/A | PD |
| Tonsil | Positive | N/A | N/A | SD |
| Ileum | Positive | N/A | N/A | PR |
| Uterine Sarcoma | Positive | Positive | 2+ 95% | 4 muts/Mb | SD |
| Vulvar | Positive | CPS < 1 0 | 4.2 muts/Mb | SD |
| Vaginal | Positive | N/A | N/A | PD |
| Ovarian | Positive | 0%, Negative | 4 muts/Mb | PD |
| Endometrial | Positive | N/A | N/A | PD |
| Ovarian | Positive | N/A | N/A | PD |
| Endometrial | Positive | N/A | N/A | SD |
| Endometrial | Positive | N/A | N/A | PD |
| Endometrial | Positive | CPS 3; 0% in older test | 4 muts/Mb | PD |
| Endometrial Carcinosarcoma | Positive | Negative|0% | 8 muts/Mb | PD |