Fig. 8.

Construction of a nomogram risk model of paediatric neuroblastoma based on age and TP53 CCNE1, CDK2, CHEK2 and SESN1 expression. a The nomogram model based on age and TP53 CCNE1, CDK2, CHEK2 and SESN1 expression levels in the E-MTAB-161, E-MTAB-8248, E-TABM-38, GSE16476 and GSE49710 datasets. b Kaplan–Meier curves showing the different overall survival rates of paediatric neuroblastoma patients between the low-risk subgroup and the high-risk subgroup. c The ROC curves showed the predictive specificity and sensitivity of the nomogram model. The AUC was calculated in the prediction of the three-year, five-year or ten-year overall survival of paediatric neuroblastoma