Table 1.
Mean and standard deviation in all group and in tertiles of LASr
| Variable | Total cohort | Group 1 (n=33) LASr ≤7% | Group 2 (n=32) LASr 8-13% | Group 3 (n=32) LASr ≥14% | P |
|---|---|---|---|---|---|
| Meeting guideline criteria for intervention based on echo data, n (%) | |||||
| Afib/SR | 37/60 (38.1) | 24/9 (72.7) | 11/21 (34.4) | 2/30 (6.2) | 0.0001 |
| PASP (mmHg) ≥50/<50 | 21/76 (21.6) | 13/20 (39.4) | 6/26 (18.7) | 2/30 (6.2) | 0.005 |
| Meeting criteria for intervention No/yes | 46/51 (58.7) | 4/28 (87.5) | 14/18 (56) | 28/4 (12.5) | 0.0001 |
| Age (years) | 47.4±11.9 | 50.4±13.6 | 48.4±12.3 | 43.7±9.1 | 0.07 |
| Male/female | 30/67 | 11/22 | 13/19 | 6/26 | 0.1 |
| SBP (mmHg) | 120.8±17.8 | 122±19.8 | 125±18 | 115±15.3 | 0.09 |
| DBP (mmHg) | 69.6±12.2 | 68±13.8 | 73±12.4 | 67±12.4 | 0.07 |
| HR (bpm) | 72.3±12.8 | 77±12 | 72±14 | 67±10 | 0.008 |
| Mean MV gradient (mmHg) | 8.3±5.1 | 8.3±5.6 | 8.6±5.1 | 7.7±4.8 | 0.7 |
| MV area by PHT (cm2) | 1.35±0.3 | 1.35±0.38 | 1.34±0.36 | 1.35±0.33 | 0.9 |
| LVMi (g/m2) | 79.2±22.2 | 82.6±24.8 | 79.6±20.5 | 75.1±22.1 | 0.4 |
| RWT | 32.7±7.3 | 33.1±6.2 | 32.9±8.2 | 32.2±7.7 | 0.8 |
| PVR (WU) | 2.08±0.8 | 2.5±1 | 2.0±0.6 | 1.6±0.4 | 0.0001 |
| Right S` (cm/s) | 10.5±2.5 | 8.9±1.8 | 11.3±2.4 | 11.5±2.4 | 0.0001 |
| RV FAC (%) | 35.6±9.1 | 32±9.7 | 38±10.6 | 36±5.7 | 0.02 |
| RV systolic area (cm2) | 10.59±3.2 | 11.11±3.2 | 10.4±3.7 | 10.2±2.6 | 0.5 |
| RV-fwLG/PASP (no 10 patients with severe TR) | 0.63±0.4 | 0.48±0.4 | 0.62±0.5 | 0.78±0.4 | 0.05 |
| TAPSE/PASP (no 10 patients with severe TR) | 0.71±0.5 | 0.56±0.5 | 0.72±0.47 | 0.85±0.53 | 0.1 |
| LASr (%) | 11.18±6.4 | 4.7±1.9 | 10.25±2 | 18.8±4 | 0.0001 |
| LA volume systole (ml) | 128.3±48.3 | 146.9±54.1 | 133.5±43 | 104.7±37.4 | 0.001 |
| LA volume diastole (ml) | 103.9±48.4 | 135±51.8 | 106.7±37.6 | 70±30 | 0.0001 |
| LA EF (%) | 20.1±12.5 | 8.35±5.4 | 18.58±6.7 | 32.25±8.9 | 0.0001 |
| SVR dynamic (s/cm5) | 1.77±0.69 | 1.97±0.66 | 1.65±0.8 | 1.69±0.45 | 0.1 |
BP: Blood pressure, SBP: Systolic BP, DBP: Diastolic BP, HR: Heart rate, MV: Mitral valve, PHT: Pressure half time, LVMi: Left ventricular mass index, RWT: Relative wall thickness, AFib: Atrial fibrillation, SR: Sinus rhythm, PASP: Pulmonary artery systolic pressure, PVR: Pulmonary vascular resistance, RV: Right ventricular, FAC: Fractional area change, RV-fwLG: Right ventricular-free wall longitudinal strain; LA: Left atrium, SVR: Systemic vascular resistance, EF: Ejection fraction, TR: Tricuspid regurgitation, TAPSE: Tricuspid annular plain systolic excursion, LASr: left atrium reservoir strain