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. 2022 Jun 1;117:e200444. doi: 10.1590/0074-02760200444

TABLE III. Trypanosoma cruzi recombinant proteins/synthetic peptides for rapid diagnostics tests and epidemiological studies.

Applications Antigen name Corresponding protein
Acute / congenital infections SAPA / TCNA / TS Trans-sialidases family
Acute /Chronic infections Ag36 / JL9 / MAP Microtubule-associated protein
Chronic infection B13 / Ag2 / TCR39 / PEP2 / TSSA Trypomastigote surface protein
CRA / Ag30 / JL8 / TCR27 Cytoplasmatic antigen
FRA / Ag1 / JL7 / H49 Cytoskeleton-associated protein
FcaBP / 1F8 / Tc-24 / Tc-28 Flagellar Ca++ binding protein
TcE / JL5 / TcP0 Ribosomal proteins
cy-hsp70 / mt-hsp70 / grp-hsp78 Heat shock proteins
FL160 / CEA / CRP Flagellum-associated surface protein protein
SAPA, Ag 1, 2, 13, 30, 36, KMP11, HSP70, PFR2, Tgp63 Antigens used in grouped panels

CRA: cytoplasmatic repetitive antigen; FRA: flagellar repetitive antigen; MAP: microtubule associated protein; SAPA: shed acute-phase antigen; CEA: chronic axoantigen; CRP: complement regulatory protein; cy-hsp: cytoplasmatic heat shock protein; grp-hsp: endoplasmatic reticulum heat shock protein; mt-hsp: mitochondrion heat shock protein; TCNA: Trypanosoma cruzi neuraminidase; TS: trans-sialidase; TSSA: trypomastigote small surface antigen. Several different antigen names given to identical or similar recombinant antigens or peptides are grouped as x/y/z.