Table 1.
Genes Upregulated in P4 but Downregulated in Baicalein Treatment
| Gene Symbol | Entrez ID | Description | Fold Change | p Value | FDR Adj p Value |
|---|---|---|---|---|---|
| Plin4 | 57435 | perilipin 4 | −1.43 | 3.03E-08 | 5.77E-05 |
| Zbtb16 | 235320 | zinc finger and BTB domain containing 16 | −1.35 | 3.75E-06 | 2.28E-03 |
| Tcf23 | 69852 | transcription factor 23 | −1.14 | 1.94E-08 | 4.20E-05 |
| Nexn | 68810 | nexilin | −1.13 | 7.41E-07 | 6.11E-04 |
| Fam107a | 268709 | family with sequence similarity 107, member A | −1.11 | 1.32E-04 | 2.67E-02 |
| Gnao1 | 14681 | guanine nucleotide binding protein, alpha O | −1.07 | 3.74E-05 | 1.14E-02 |
| Mir145a | 387163 | microRNA 145a | −1.07 | 3.88E-04 | 4.12E-02 |
| Cytl1 | 231162 | cytokine-like 1 | −1.07 | 1.79E-04 | 2.84E-02 |
| Ccdc187 | 329366 | coiled-coil domain containing 187 | −1.05 | 1.15E-04 | 2.49E-02 |
| Npas4 | 225872 | neuronal PAS domain protein 4 | −1.05 | 2.14E-07 | 2.32E-04 |
| Bvht | 545261 | braveheart long non-coding RNA | −1.03 | 4.63E-06 | 2.43E-03 |
| Jph2 | 59091 | junctophilin 2 | −1.01 | 4.19E-05 | 1.22E-02 |
| Asb2 | 65256 | ankyrin repeat and SOCS box-containing 2 | −0.99 | 1.39E-04 | 2.70E-02 |
| Slit3 | 20564 | slit homolog 3 (Drosophila) | −0.98 | 2.23E-05 | 7.57E-03 |
| Ptger3 | 19218 | prostaglandin E receptor 3 (subtype EP3) | −0.96 | 1.82E-04 | 2.84E-02 |
| Ptprb | 19263 | protein tyrosine phosphatase, receptor type, B | −0.94 | 7.24E-05 | 1.68E-02 |
| Fstl3 | 83554 | follistatin-like 3 | −0.93 | 4.19E-04 | 4.32E-02 |
| Cdr2 | 12585 | cerebellar degeneration-related 2 | −0.91 | 2.68E-04 | 3.44E-02 |
| Itga7 | 16404 | integrin alpha 7 | −0.90 | 1.50E-04 | 2.70E-02 |
| Hspb7 | 29818 | heat shock protein family, member 7 (cardiovascular) | −0.89 | 1.23E-04 | 2.59E-02 |
| Mn1 | 433938 | meningioma 1 | −0.89 | 1.47E-04 | 2.70E-02 |
| Ccdc69 | 52570 | coiled-coil domain containing 69 | −0.89 | 1.55E-04 | 2.74E-02 |
| Tubb6 | 67951 | tubulin, beta 6 class V | −0.87 | 2.09E-04 | 2.96E-02 |
| Pdlim3 | 53318 | PDZ and LIM domain 3 | −0.86 | 3.98E-04 | 4.20E-02 |
| Speg | 11790 | SPEG complex locus | −0.86 | 1.82E-06 | 1.31E-03 |
| Smoc2 | 64074 | SPARC related modular calcium binding 2 | −0.85 | 5.45E-04 | 4.98E-02 |
| Fam212b | 109050 | family with sequence similarity 212, member B | −0.82 | 2.63E-04 | 3.41E-02 |
| Clmp | 71566 | CXADR-like membrane protein | −0.81 | 3.51E-04 | 3.95E-02 |
| Prkca | 18750 | protein kinase C, alpha | −0.80 | 8.95E-05 | 2.01E-02 |
| S1pr1 | 13609 | sphingosine-1-phosphate receptor 1 | −0.79 | 2.64E-04 | 3.41E-02 |
| Igsf9b | 235086 | immunoglobulin superfamily, member 9B | −0.76 | 2.00E-04 | 2.90E-02 |
| Wipf3 | 330319 | WAS/WASL interacting protein family, member 3 | −0.73 | 2.65E-05 | 8.82E-03 |
| Gja4 | 14612 | gap junction protein, alpha 4 | −0.70 | 1.47E-04 | 2.70E-02 |
| Neurl1a | 18011 | neuralized E3 ubiquitin protein ligase 1A | −0.69 | 3.69E-04 | 4.02E-02 |
| Dmpk | 13400 | dystrophia myotonica-protein kinase | −0.68 | 2.61E-04 | 3.41E-02 |
| Col6a3 | 12835 | collagen, type VI, alpha 3 | −0.64 | 2.76E-04 | 3.50E-02 |
| Myrip | 245049 | myosin VIIA and Rab interacting protein | −0.64 | 1.34E-04 | 2.67E-02 |
| Thbs3 | 21827 | thrombospondin 3 | −0.61 | 6.15E-05 | 1.50E-02 |
| Msn | 17698 | moesin | −0.56 | 1.63E-04 | 2.83E-02 |
| Ehbp1l1 | 114601 | EH domain binding protein 1-like 1 | −0.55 | 1.70E-05 | 6.39E-03 |
| Esyt2 | 52635 | extended synaptotagmin-like protein 2 | −0.54 | 2.77E-04 | 3.50E-02 |
| Ppp1r12c | 232807 | protein phosphatase 1, regulatory subunit 12C | −0.53 | 2.73E-05 | 8.93E-03 |
| Cap2 | 67252 | CAP, adenylate cyclase-associated protein, 2 (yeast) | −0.50 | 4.66E-04 | 4.57E-02 |
| Tgm2 | 21817 | transglutaminase 2, C polypeptide | −0.48 | 3.10E-04 | 3.65E-02 |