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The structure and genome organization of SARS-CoV-2. (A) Four structural proteins in SARS-CoV-2 are the spike (S), envelope (E), nucleocapsid (N) and membrane (M). S, E and M are embedded in the lipid bilayer envelope while RNA are coated by N. (B) The genome of SARS-CoV-2 consists of 13-15 open reading frames and encodes protein which plays important role in binding and translation between the virus and the host cell.
