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. 2022 Mar 22;67(2):878–891. doi: 10.1007/s11686-022-00530-8

Table 4.

Biochemical analysis of serum collected from mice administered five times oral dose of 844 mg/kg zinc oxide nanoparticles for 5 consecutive days

Group ALP (U/l) ALT (U/l) Creatinine (mg/dl)
ZnO NPs 94.3 ± 17.3 86.6 ± 14.74 0.40 ± 0.00
Control 85 ± 5.7 67.0 ± 9.60 0.33 ± 0.033
Solvent control 74.0 ± 13.0 41.6 ± 7.17 0.40 ± 0.00
F2,6 1.644 4.226 4.000
P NS NS NS

ALP alkaline phosphatase, ALT alanine aminotransferase

NS Non-significant (P > 0.05)