Table 5.
Author | Year | Agent | Dose | n | Radiation regimen | Results |
---|---|---|---|---|---|---|
Kleinberg et al. [37] | 1999 | Efaproxiral | 100 mg/kg iv over 1 h before RT | 19 | 60 Gy in 30 fractions |
Treatment was well tolerated Increased oxygen unloading |
Kleinberg et al. [38] | 2002 | Efaproxiral | 100 mg/kg iv over 30 min before RT | 50 | 60 Gy in 30 fractions | Median OS: 12.3 months |
n = number of patients included (number of patients with glioblastoma in parentheses if multiple entities were included)