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. 2022 May 3;198(6):507–526. doi: 10.1007/s00066-022-01942-1

Table 5.

Trials evaluating efaproxiral as radiosensitizer, sorted by publication year

Author Year Agent Dose n Radiation regimen Results
Kleinberg et al. [37] 1999 Efaproxiral 100 mg/kg iv over 1 h before RT 19 60 Gy in 30 fractions

Treatment was well tolerated

Increased oxygen unloading

Kleinberg et al. [38] 2002 Efaproxiral 100 mg/kg iv over 30 min before RT 50 60 Gy in 30 fractions Median OS: 12.3 months

n = number of patients included (number of patients with glioblastoma in parentheses if multiple entities were included)