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. 2022 May 3;198(6):507–526. doi: 10.1007/s00066-022-01942-1

Table 6.

Trials evaluating tirapazamine as radiosensitizer

Author Year Agent Dose n Radiation regime Results
Del Rowe et al. [39] 2000 Tirapazamine

159 or 260 mg/m2

3 × a week, 12 × overall

124 60 Gy in 30 fractions

Median OS: 10.8 months (159 mg/m2)

vs 9.5 months (260 mg/m2)

n = number of patients included (number of patients with glioblastoma in parentheses if multiple entities were included)