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. 2022 May 3;198(6):507–526. doi: 10.1007/s00066-022-01942-1

Table 9.

Trials evaluating motexafin gadolinium (MGd) as a radiosensitizer, sorted by publication year

Author Year Agent Dose n Radiation regimen Results
Ford et al. [67] 2007 Motexafin Gadolinium 10–22 × 4–5.2 mg/kg/day 33 59.4 Gy in 33 fractions

MTD: 5 mg/kg/day

Median OS: 16.1 months

Bachman et al. [70] 2015 Motexafin Gadolinium 3–5 mg/kg daily pre RT 118 60 Gy in 30 fractions

MTD MGd: 5 mg/kg/day

Median OS: 15.6 months

RT + MGd + TMZ was well tolerated

+ TMZ 75 mg/m2/day

n = number of patients included (number of patients with glioblastoma in parentheses if multiple entities were included)