Table 9.
Author | Year | Agent | Dose | n | Radiation regimen | Results |
---|---|---|---|---|---|---|
Ford et al. [67] | 2007 | Motexafin Gadolinium | 10–22 × 4–5.2 mg/kg/day | 33 | 59.4 Gy in 33 fractions |
MTD: 5 mg/kg/day Median OS: 16.1 months |
Bachman et al. [70] | 2015 | Motexafin Gadolinium | 3–5 mg/kg daily pre RT | 118 | 60 Gy in 30 fractions |
MTD MGd: 5 mg/kg/day Median OS: 15.6 months RT + MGd + TMZ was well tolerated |
+ TMZ | 75 mg/m2/day |
n = number of patients included (number of patients with glioblastoma in parentheses if multiple entities were included)