Table 7.
Sensitivity comparison between LFA and icELISA
| Analyte | LFA determination range/LOD | icELISA determination range/LOD |
|---|---|---|
| Ginsenosides Rb1 and Rg1 | 2 μg/mL for both analytes | Ginsenoside Rb1 and Rg1 are 20–400 ng/mL [107] and 0.3–10 µg/mL [108], respectively |
| Sennosides A and B | 125 ng/mL for both analytes | Sennoside A and sennoside B are 20–200 ng/mL [109] and 0.5–15 ng/mL [110], respectively |
| Glycyrrhizin | 250 ng/mL | 20–200 ng/mL [111] |
| Glycyrrhizin | 20–50 ng/ml | 0.2–5.1 ng/mL [97] |
| Pseudojujubogenin glycosides | 125 ng/mL | 1.95–62.5 ng/mL; 0.5 ng/mL [112] |
| Asiaticoside | 12.5 μg/mL | 0.78–50 µg/mL; 6.2 µg/mL [113] |
| Baicalin | 0.6 μg/mL | 200 ng/mL–2 µg/mL; 100 ng/mL [114] |
| Ginsenoside Re | 200 µg/L | 0.08–0.7 µg/mL [114] |
| Morphine | 1 ng/mL | N/A |
| Mulberroside A | 2 µg/mL | 0.17–15.62 μg/mL [115] |
| Puerarin | 1–10 μg/mL; 5.8 ng/mL | 10 ng/mL–1 μg/mL; 181.3 ng/mL [37] |
| Daidzin and genistin | 125 ng/mL | 1.95–62.5 ng/mL; 1.95 ng/mL [116] |
| Miroestrol | 0.156 µg | 10–780 ng/mL; 3.5 ng/mL [117] |
| Harringtonine | 39.1–313 ng/mL; 313 ng/mL | 0.76–48.8 ng/mL; 0.76 ng/mL [118] |
| Monocrotaline | 0.61 ng/mL | 48.8 pg/mL–3.13 ng/mL [119] |
| Mitragynine | 1 mg/mL of mitragynine by visual assessment and 0.60 mg/mL by Image J analysis | 32.92–250 μg/mL; 32.47 μg/mL [120] |
| Salvinorin A | 0.625 µg/mL | 0.0195–0.625 μg/mL; 0.0195 μg/mL [121] |
| Miroestrol and puerarin | Miroestrol and puerarin are 0.15 μg and 4.5 μg, respectively | Miroestrol and puerarin are 10–780 ng/mL; 3.5 ng/mL [117] and 0.02–12.5 μg/mL; 0.02 μg/mL [122], respectively |
| Saikosaponin d | 96 ng/mL–150 µg/mL | 156.25 to 5000.00 ng/mL; 148.41 ng/mL [123] |
| Mitragynine and 7-hydroxymitragynine | 0.16–5 μg/mL | 0.047–6 μg/mL [101] |
| Icariin | 500 ng/mL | 5–3125 ng/mL; 8.41 ng/mL [40] |
| Isomiroestrol | 7.0 µg/mL | 390–12,500 ng/mL; 323 ng/mL [124] |
| Triptolide | 1 μg/mL | N/A |
| Aristolochic acid I | 0.25 μg/g | IC50 = 5.02 ng/mL [47] |
| Aconitine | 10–25 ng/mL | 1.13–11.76 ng/mL [29] |
| Rhein | 80–5000 ng/mL; 98.2 ng/mL | 5–3125 ng/mL; 8.41 ng/mL [42] |
| Kwakhurin | 160 ng/mL | 1.53–48.8 ng/mL; 1.13 ng/mL [125] |
| (S)-Higenamine | 156 ng/mL | 7.81–125 ng/mL; 4.41 ng/mL [126] |
| Amarogentin | 31.25–500 ng/mL; 250 ng/mL | 1.95–62.5 ng/mL; 1.28 ng/mL [95] |
| Colchicine | 1–25 ng/mL in milk, 2.5–50 ng/mL in beef, 1–25 ng/mL in edible lily, and 2.5–25 ng/mL in daylily | 0.09–2.16 ng/mL [44] |
| Deoxymiroestrol | 250 ng/mL | 31.25–1,000 ng/mL; 30.80 ng/mL [127] |