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. 2022 Apr 11;49(7):2300–2309. doi: 10.1007/s00259-022-05785-x

Table 1.

Physical characteristics of the commonly used theranostics pairs 68 Ga/177Lu and 68 Ga/90Y

Radionuclides Physical characteristics* Pharmaceuticals Use
Energy [keV] Half-life
Gamma Beta or Alpha
68Ga 511 (caused by annihilation) 1899 (β+) 1.13 h

[68Ga]Ga-PSMA-11

[68Ga]Ga-PSMA-I&T

[68Ga]Ga-DOTA-TATE (NETSPOT ™)

[68Ga]Ga-DOTA-TOC (SomaKIT TOC ®)

Diagnostic
18F 511 (caused by annihilation) 634 (β+) 1.83 h

Piflufolastat F18 (Pylarify®)

[18F]F PSMA-1007

[18F]DCFPyL

177Lu

113 (6%)

208 (11%)

498 (β) 6.73 d

[177Lu]Lu-PSMA-617

[177Lu]Lu-PSMA-I&T

[177Lu]Lu-DOTA-TATE (Lutathera®)

Therapy
90Y Bremsstrahlung 2280 (β) 2.67 d [90Y]Y-DOTA-TOC
99mTc 140 (89%) not relevant 6.01 h

[99mTc]Tc-MDP

[99mTc]Tc-DPD

[99mTc]Tc-HDP

Diagnostic
223Ra

154 (6%)

269 (14%)

5716 (α), 5606 (α), 6819 (α), 7386 (α), 6623 (α)

1370 (β)

1420 (β)

11.44 d 223RaCl2 (Xofigo ®) Therapy

*Data are extracted from The Lund/LBNL Nuclear Data Search V 2.0 (http://nucleardata.nuclear.lu.se/toi/)

Without claim to completeness