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. 2022 Apr 29;17(12):2717–2724. doi: 10.4103/1673-5374.339489

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Differential expression of microRNAs between bMSCs and exosomes.

(A) Heatmap of differentially expressed microRNAs between bMSCs and exosomes. The relative expression levels of hundreds of detected microRNAs were displayed in the heatmap. The intensity of the color indicates the expression of microRNAs, with a darker color meaning higher expression level. (B) Volcano plot of the differentially expressed microRNAs. Blue represents low expression while red denotes high expression in exosomes. Gray denotes lack of differences between them. (C) The differentially expressed microRNAs in vivo. Data are expressed as mean ± SD (n = 5 per group). *P < 0.05 (one-way analysis of variance followed by the least significant difference test). bMSCs: Bone marrow mesenchymal stem cells; Exo: exosome; mmu: musmusculus; TBI: traumatic brain injury.