Additional Table 1.
Common differentially expressed genes in the three groups
| Gene ID(Ensembl database) | Gene name | HBO/SH | HBO/SCI | SCI/SH | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Fold change | P-value | Fold change | P-value | Fold change | P-value | ||
| ENSMUSG00000020427 | Igfbp3 | 5.57 | 4.40E-27 | 0.57 | 0.002169 | 9.81 | 5.84E-27 |
| ENSMUSG00000025650 | Col7a1 | 7.85 | 7.87E-23 | 0.55 | 0.015444 | 14.39 | 1.53E-20 |
| ENSMUSG00000005413 | Hmox1 | 4.88 | 2.49E-19 | 0.42 | 0.001936 | 11.70 | 5.60E-16 |
| ENSMUSG00000028364 | Tnc | 4.34 | 3.13E-19 | 0.58 | 0.006950 | 7.49 | 5.35E-17 |
| ENSMUSG00000042379 | Esm1 | 10.99 | 4.00E-16 | 0.62 | 0.042197 | 17.70 | 1.17E-21 |
| ENSMUSG00000050708 | Ftl1 | 3.40 | 5.42E-14 | 0.61 | 0.010553 | 5.61 | 2.68E-26 |
| ENSMUSG00000062382 | Gm10116 | 3.96 | 1.55E-13 | 0.62 | 0.024333 | 6.43 | 2.18E-26 |
| ENSMUSG00000025473 | Adam8 | 5.34 | 6.15E-13 | 0.60 | 0.040891 | 8.90 | 2.19E-16 |
| ENSMUSG00000030208 | Emp1 | 4.16 | 6.44E-10 | 0.58 | 0.017200 | 7.20 | 9.89E-26 |
| ENSMUSG00000026938 | Fcna | 7.34 | 2.89E-09 | 0.55 | 0.020858 | 13.32 | 6.95E-14 |
| ENSMUSG00000026208 | Des | 4.15 | 3.40E-09 | 0.33 | 0.003008 | 12.68 | 1.14E-10 |
| ENSMUSG00000026228 | Htr2b | 5.97 | 3.83E-09 | 0.52 | 0.005843 | 11.47 | 5.26E-20 |
| ENSMUSG00000029373 | Pf4 | 6.14 | 3.88E-09 | 0.54 | 0.017480 | 11.46 | 2.36E-16 |
| ENSMUSG00000068220 | Lgals1 | 3.28 | 5.20E-09 | 0.60 | 0.015061 | 5.48 | 5.66E-15 |
| ENSMUSG00000030787 | Lyve1 | 6.97 | 2.06E-08 | 0.56 | 0.036853 | 12.54 | 7.27E-10 |
| ENSMUSG00000050370 | Ch25h | 4.09 | 2.27E-08 | 0.64 | 0.033780 | 6.37 | 1.03E-12 |
| ENSMUSG00000094338 | Hist1h2bl | 4.61 | 5.96E-08 | 0.60 | 0.043563 | 7.69 | 1.34E-11 |
| ENSMUSG00000016356 | Col20a1 | 2.58 | 1.00E-07 | 0.64 | 0.000405 | 4.02 | 1.73E-16 |
| ENSMUSG00000032085 | Tagln | 3.10 | 3.32E-07 | 0.63 | 0.022431 | 4.92 | 1.25E-09 |
| ENSMUSG00000006219 | Fblim1 | 3.38 | 5.65E-07 | 0.65 | 0.037851 | 5.19 | 1.63E-19 |
| ENSMUSG00000001025 | S100a6 | 2.26 | 1.35E-06 | 0.62 | 0.018226 | 3.67 | 1.58E-11 |
| ENSMUSG00000020377 | Ltc4s | 2.97 | 4.01E-06 | 0.66 | 0.044896 | 4.49 | 1.64E-11 |
| ENSMUSG00000028464 | Tpm2 | 2.21 | 6.88E-06 | 0.53 | 0.045645 | 4.20 | 1.02E-05 |
| ENSMUSG00000030867 | Plk1 | 2.89 | 7.46E-06 | 0.54 | 0.013798 | 5.34 | 5.11E-11 |
| ENSMUSG00000105954 | Gm42793 | 3.81 | 9.82E-06 | 0.54 | 0.044318 | 7.04 | 1.03E-10 |
| ENSMUSG00000025701 | Alox5 | 2.46 | 6.32E-05 | 0.60 | 0.008067 | 4.09 | 4.72E-12 |
| ENSMUSG00000025270 | Alas2 | 1.97 | 0.000132 | 0.56 | 0.029812 | 3.50 | 3.65E-06 |
| ENSMUSG00000055775 | Myh8 | 5.29 | 0.000156 | 0.21 | 0.005358 | 24.99 | 9.25E-08 |
| ENSMUSG00000069300 | Hist1h2bj | 2.48 | 0.000209 | 0.52 | 0.003955 | 4.79 | 8.12E-12 |
| ENSMUSG00000031097 | Tnni2 | 5.04 | 0.000272 | 0.36 | 0.037796 | 14.10 | 4.45E-05 |
| ENSMUSG00000051747 | Ttn | 3.40 | 0.000415 | 0.18 | 0.003850 | 19.10 | 2.04E-07 |
| ENSMUSG00000000901 | Mmp11 | 2.30 | 0.000483 | 0.58 | 0.026619 | 3.95 | 1.02E-07 |
| ENSMUSG00000049699 | Ucn2 | 5.11 | 0.000553 | 0.46 | 0.027000 | 11.02 | 7.36E-07 |
| ENSMUSG00000037725 | Ckap2 | 1.86 | 0.000623 | 0.65 | 0.025747 | 2.87 | 2.35E-08 |
| ENSMUSG00000060470 | Adgrg3 | 3.78 | 0.000658 | 0.49 | 0.011925 | 7.68 | 5.28E-09 |
| ENSMUSG00000052305 | Hbb-bs | 1.50 | 0.000741 | 0.43 | 0.001689 | 3.49 | 2.59E-06 |
| ENSMUSG00000034457 | Eda2r | 2.18 | 0.000841 | 0.57 | 0.015200 | 3.79 | 5.56E-09 |
| ENSMUSG00000068744 | Psrc1 | 2.28 | 0.001477 | 0.61 | 0.045358 | 3.77 | 1.03E-06 |
| ENSMUSG00000037139 | Myom3 | 4.86 | 0.001778 | 0.27 | 0.017661 | 17.74 | 2.81E-06 |
| ENSMUSG00000017300 | Tnnc2 | 5.61 | 0.001799 | 0.32 | 0.030543 | 17.31 | 7.03E-06 |
| ENSMUSG00000027559 | Car3 | 2.59 | 0.001862 | 0.38 | 0.036141 | 6.76 | 5.02E-05 |
| ENSMUSG00000004951 | Hspb1 | 1.87 | 0.001919 | 0.64 | 0.021352 | 2.94 | 6.38E-08 |
| ENSMUSG00000026407 | Cacna1s | 4.63 | 0.002017 | 0.35 | 0.044762 | 13.26 | 0.000101 |
| ENSMUSG00000060093 | Hist1h4a | 2.21 | 0.002602 | 0.53 | 0.014364 | 4.13 | 2.89E-06 |
| ENSMUSG00000030730 | Atp2a1 | 3.77 | 0.002754 | 0.22 | 0.021344 | 17.33 | 6.99E-06 |
| ENSMUSG00000049134 | Nrap | 1.76 | 0.003589 | 0.38 | 0.008269 | 4.61 | 5.69E-05 |
| ENSMUSG00000026950 | Neb | 2.86 | 0.003815 | 0.15 | 0.001650 | 19.08 | 2.88E-07 |
| ENSMUSG00000028195 | Cyr61 | 1.62 | 0.004419 | 0.65 | 0.018046 | 2.48 | 1.31E-06 |
| ENSMUSG00000020061 | Mybpc1 | 1.66 | 0.005029 | 0.41 | 0.003256 | 4.02 | 2.58E-06 |
| ENSMUSG00000031972 | Acta1 | 3.68 | 0.005198 | 0.17 | 0.008071 | 21.66 | 9.24E-07 |
| ENSMUSG00000061723 | Tnnt3 | 3.97 | 0.006093 | 0.31 | 0.027373 | 12.83 | 2.54E-05 |
| ENSMUSG00000027022 | Xirp2 | 3.25 | 0.006723 | 0.10 | 0.000941 | 31.83 | 1.52E-06 |
| ENSMUSG00000037966 | Ninj1 | 1.53 | 0.007674 | 0.62 | 0.013293 | 2.46 | 2.35E-06 |
| ENSMUSG00000034413 | Neurl1b | 1.89 | 0.011064 | 0.53 | 0.013293 | 3.54 | 1.25E-06 |
| ENSMUSG00000030905 | Crym | 2.22 | 0.011362 | 0.38 | 0.000416 | 5.81 | 1.03E-07 |
| ENSMUSG00000098132 | Rassf10 | 1.62 | 0.011696 | 0.60 | 0.003982 | 2.70 | 2.28E-08 |
| ENSMUSG00000015468 | Notch4 | 1.61 | 0.012422 | 0.63 | 0.018171 | 2.57 | 1.57E-05 |
| ENSMUSG00000073940 | Hbb-bt | 1.51 | 0.015031 | 0.47 | 0.006031 | 3.20 | 1.33E-05 |
| ENSMUSG00000050234 | Gja4 | 1.77 | 0.016063 | 0.64 | 0.048328 | 2.76 | 9.55E-06 |
| ENSMUSG00000020475 | Pgam2 | 8.72 | 0.017905 | 0.20 | 0.010411 | 43.88 | 3.05E-06 |
| ENSMUSG00000046295 | Ankle1 | 1.91 | 0.017993 | 0.59 | 0.031139 | 3.25 | 5.75E-06 |
| ENSMUSG00000043085 | Tmem82 | 1.98 | 0.022230 | 0.48 | 0.012129 | 4.17 | 8.02E-06 |
| ENSMUSG00000021367 | Edn1 | 1.74 | 0.025682 | 0.55 | 0.020034 | 3.16 | 8.17E-06 |
| ENSMUSG00000022769 | Sdf2l1 | 1.53 | 0.031715 | 0.65 | 0.024352 | 2.36 | 4.93E-06 |
| ENSMUSG00000006221 | Hspb7 | 1.89 | 0.036322 | 0.22 | 0.001287 | 8.58 | 1.92E-05 |
| ENSMUSG00000022218 | Tgm1 | 1.50 | 0.040740 | 0.59 | 0.000973 | 2.54 | 7.40E-06 |
| ENSMUSG00000067455 | Hist1h4j | 1.98 | 0.045598 | 0.52 | 0.034938 | 3.83 | 7.29E-06 |
| ENSMUSG00000096458 | Moap1 | 0.22 | 2.51E-06 | 35.58 | 8.03E-14 | 0.01 | 5.14E-28 |
| ENSMUSG00000045349 | Sh2d5 | 0.37 | 1.09E-05 | 1.73 | 0.016555 | 0.21 | 4.10E-14 |
| ENSMUSG00000056423 | Uts2b | 0.22 | 1.57E-05 | 3.76 | 0.044830 | 0.06 | 7.51E-12 |
| ENSMUSG00000023945 | Slc5a7 | 0.50 | 0.000199 | 1.63 | 0.027411 | 0.31 | 1.25E-11 |
| ENSMUSG00000021680 | Crhbp | 0.46 | 0.001344 | 1.89 | 0.046309 | 0.24 | 1.57E-08 |
| ENSMUSG00000005268 | Prlr | 0.49 | 0.002342 | 3.47 | 2.40E-05 | 0.14 | 6.64E-25 |
| ENSMUSG00000031285 | Dcx | 0.66 | 0.007058 | 1.51 | 0.021917 | 0.44 | 9.26E-07 |
| ENSMUSG00000062561 | Gm10118 | 0.64 | 0.016936 | 1.56 | 0.036242 | 0.41 | 1.57E-06 |
| ENSMUSG00000025529 | Zfp711 | 0.66 | 0.024679 | 1.66 | 0.011823 | 0.40 | 1.30E-07 |
Gene ID comes from Ensembl database. EdgeR was used to analyse the differentially expressed genes among the three groups. HBO: Hyperbaric oxygen; SCI: spinal cord injury; SH: sham.