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. Author manuscript; available in PMC: 2023 Jul 5.
Published in final edited form as: Eur J Med Chem. 2022 Apr 27;237:114407. doi: 10.1016/j.ejmech.2022.114407

Table 4.

Antiproliferative activity EC50 (μM) of compounds 29 and 6.

Cpd-29 Cpd-6 A-485
MCF-7 5.3 ± 0.1 >20 >30 14
MDA-MB231 8.5 ± 0.5 >20 >10 15
LNCaP 6.2 ± 0.4 >20 0.26 15
PC-3 4.4 ± 1.0 >20 2.1 15
PANC-1 1.2 ± 0.2 >20 >30 14
MDA-PANC-28 4.3 ± 0.4 >20 >30 14
Melm-13 3.6 ± 0.4 >20 0.35 15
MV4;11 8.7 ± 0.6 >20 0.26 30
RPMI-8226 6.4 ± 1.5 >20 0.16 15