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. 2022 May 20;12:837205. doi: 10.3389/fcimb.2022.837205

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Copyright © 2022 Chen, Wu, Zeng, Chen, Li, Li, He and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diversity and abundance analysis. The alpha diversity [Shannon (A), Simpson (B)] based on operational taxonomic unit (OTU) abundance for the sham, UUO, and UUO+FZHY groups. (C) The beta diversity shows the PCoA plot of UniFrac distances. (D) The top 10 high relative abundance for the sham, UUO, and UUO+FZHY groups. The difference of abundance at the genus level in the sham group compared with the UUO group (E) and the UUO group compared with the UUO+FZHY group (F). The difference of abundance at the genus level in the sham group compared with the UUO group (G) and the UUO group compared with the UUO+FZHY group (H). Wilcoxon rank-sum test was used to compare the difference in diversity between the two groups in the boxplot. t-test was used to compare the difference in abundance between the two groups; P <0.05 is considered to be a significant difference.