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. Author manuscript; available in PMC: 2022 Jun 4.
Published in final edited form as: Cell Metab. 2021 Oct 21;33(11):2201–2214.e11. doi: 10.1016/j.cmet.2021.10.001

Fig 1. Type 2 diabetes is associated with degenerative remodeling.

Fig 1.

A, Work-flow of study 1 (biopsies from m. Vastus Lateralis) of overweight subjects (n=7), T2D (n=7) and insulin treated T2D (n=6); B, Biological processes altered in itT2D; C, Enriched pathways in itT2D; D, COL1A1 E, COL3A1; F, COL6A1; G, TGFB1 mRNA expression in OBS, T2D and itT2D; H+I, IHC staining of Collagen1, WGA and Perilipin1 from patients with (H) and without T2DM (I); J, PDGFRα expression (study 1). *p<0.05.